Set up the physical.
This is very important. All of the younger children need to be close by.
This frees you to guide/teach and have quality time with the children. You won't waste mental and physical energy--worrying about where someone is, if he is safe--or chasing after an escaped toddler. (Eliminates "Don't touch that." "Come back here.")
A carefree room also cuts down on chaos...and shows respect for the older children and their education. You and they can focus on learning in a quieter, more ordered setting.
--If you have little ones, be sure the room is safe. Use electrical plugs, toilet seat locks, cover sharp edges, correct any dangerous spots.
--Be sure the young 'uns stay within sight. Doors and gates...
--Have books and toys within their reach.
--Carefully situate learning areas. Place all desks close to you if the children will need help constantly.
If the darlings pester each other, separate them.
We purchased cheap bookshelves at a discount store which ended up serving three purposes.
1)great storage
2) each child had his own handy area for supplies
3) most importantly, when the shelves were properly placed between the desks, the studious little children couldn't even see each other.
In desperation, my husband and I set up desks in widely-spaced rows with the shelves in-between. It works beautifully. Our schoolroom is still that way...and I particularly like it
because all of us could still be together. One of children decided in high school to study in his room which was fine, but the rest of us stayed together.
--Keep everything you need right there. All books and supplies and equipment--globes, tapes recorders, computers, etc.